肥胖症与阻塞性睡眠呼吸暂停综合征的相关性研究.docVIP

精品论文 参考文献 肥胖症与阻塞性睡眠呼吸暂停综合征的相关性研究 王倩英 　　（商丘市第四人民医院内科 河南商丘 476100） 　　【摘要】目的：探究肥胖症与阻塞性睡眠呼吸暂停综合征（OSAS）之间的相关性。方法：选取2015年1月～12月期间我院诊治的60例OSAS患者作为研究对象，根据肥胖情况将BMI（体重指数）le;28kg/m2的27例患者分为对照组，将BMI＞28kg/m2的33例分为实验组，对两组患者进行夜间持续7h以上的多导睡眠呼吸监测，统计两组各项监测结果及OSAS严重程度，并进行对比分析。结果：实验组AHI（睡眠呼吸暂停低通气指数）、AD（呼吸暂停持续时间）、TRE（总呼吸事件）均高于对照组，MSaO2（平均血氧饱和度）、LSaO2（夜间最低血氧饱和度）均低于对照组，两组对比差异显著（P＜0.05）；实验组OSAS轻度患者比例明显小于对照组、中度和重度患者比例明显大于对照组，两组对比差异显著（P＜0.05）。结论：肥胖症可增加OSAS的发病风险、加重患者病情，是OSAS发病的危险因素之一。 　　【关键词】肥胖症；阻塞性；睡眠呼吸暂停 　　【中图分类号】R563 【文献标识码】A 【文章编号】1007-8231（2016）05-0045-02 　　 Correlation between obesity and obstructive sleep apnea syndrome 　　 Wang Qianying. Shangqiu City Fourth Peoples Hospital of Henan Shangqiu 476100,China 　　【Abstract】Objective To explore obesity and obstructive sleep apnea syndrome correlation (OSAS) between. Methods January 2015 - December period 60 cases of OSAS patients in our hospital as the research object, according to the case of 27 obese patients with BMI (body mass index) le;28kg / m2 divided into a control group, BMIgt; 28kg / m2 33 patients were divided into experimental group, two groups of patients for night continued 7h more polysomnography monitoring and statistical groups of monitoring results and OSAS severity, and were analyzed. Results The AHI (apnea-hypopnea index), AD (apnea duration), TRE (total respiratory events) were higher, MSaO2 (average oxygen saturation), LSaO2 (lowest nocturnal oxygen saturation ) were lower than the control group, a significant difference between two groups (P lt;0.05); the proportion of patients with mild OSAS experimental group was significantly lower than the control group, the proportion of moderate and severe patients was significantly higher than the control group, a significant difference between two groups (P lt;0.05 ). Conclusion Obesity increases the risk of OSAS, aggravating the patients condition, is one of the risk factors in the pathogenesis of OSAS. 　　【Key words】Obesity; Obstruc