降压治疗研究新动态回顾与展望PPT.ppt

降压治疗研究新动态 回顾与展望; ◆ 80岁以上高龄高血压 (HYVET) ◆ 高血压前期 (TROPH, PHARAO) ◆ 心房颤动 (ADVANCE post hoc);1.0;* * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * *;ADVANCE-AF 研究;100;WASID Trial (Warfarin-Aspirin Symtomatic Intracranial Disease) Relationship Between Blood Pressure and Strke Recurrence in Patients With Intracranial Arterial Stenosis;1; No. of events/patients Median Favors Favors Hazard ratio P for Per-Ind Placebo Blood pressure Per-Ind placebo (95% CI) trend All renal events All participants 1243/5569 1500/5571 0.79 (0.73 to 0.85) Baseline systolic blood pressure (mmHg) 120 134/615 167/560 113 mmHg 0.70 (0.56 to 0.88) 0.75 120-139 367/1736 431/1793 131 mmHg 0.85 (0.74 to 0.97) 140-159 439/1945 563/2003 149 mmHg 0.75 (0.66 to 0.85) ≥160 303/1273 339/1215 172 mmHg 0.81 (0.70 to 0.95) Baseline diastolic blood pressure (mmHg) 70 208/846 240/881 66 mmHg 0.84 (0.70 to 1.02) 0.85 70-79 387/1748 481/1758 75 mmHg 0.77 (0.67 to 0.88) 80-89 386/1862 479/1834 84 mmHg 0.76 (0.66 to 0.87) ≥90 262/1113 300/1098 95 mmHg 0.81 (0.69 to 0.96) All renal events, macrovascular events, all-cause death All participants 1781/5569 2064/5571 0.82 (0.77 to 0.88) Baseline systolic blood pressure (mmHg) 120 190/615 205/560 113 mmHg 0.82 (0.68 to 1.00) 0.35 120-139 527/1736 590/1793 131 mmHg 0.89 (0.79 to 1.00) 140-159 615/1945 771/2003 149 mmHg 0.77 (0.69 to 0.86) ≥160 449/1273 498/1215 172 mmHg 0.81 (0.72 to 0.93) Baseline diastolic blood pressure (mmHg) 70 304/846 352/881 66 mmHg 0.85 (0.73 to 1.00) 0.60 70-79 551/1748 637/1758 75 mmHg 0.83 (0.74 to 0.93) 80-89 554/1852 651/1834 84 mmHg 0.81 (0.72 to 0.90) ≥90 372/1113 424/1098 95 mmHg 0.81 (0.71 to 0.94);10; ◆ 降压治疗模式的历史演进 ◆ 优化联合治疗方案 ◆ 纠正噻嗪类利尿剂代谢缺点; 降压治疗模式的历史演进;1.4;Diuretics;10;