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Am J Physiol Regul Integr Comp Physiol 287: R934–R942, 2004.
First published May 20, 2004; 10.1152/ajpregu.00100.2004.
A long-term high-protein diet markedly reduces adipose
tissue without major side effects in Wistar male rats
Magali Lacroix,1 Claire Gaudichon,1 Antoine Martin,2 Ce´line Morens,1
Ve´ronique Mathe´,1 Daniel Tome´,1 and Jean-Franc¸ois Huneau1
1
Institut National de la Recherche Agronomique, Unite´ de Physiologie de la Nutrition
et du Comportement alimentaire, Institut National Agronomique Paris-Grignon, 75231 Paris cedex 05;
and 2Service d’Anatomie Pathologique, Hoˆpital Avicenne, 93000 Bobigny, France
Submitted 13 February 2004; accepted in final form 14 May 2004
Lacroix, Magali, Claire Gaudichon, Antoine Martin, Ce´line However, the medical use of a restricted-restricted diet for
Morens, Ve´ronique Mathe´, Daniel Tome´, and Jean-Franc¸ois Hu-
weight loss does not necessarily lead to a high amount of D
neau. A long-term high-protein diet markedly reduces adipose tissue o
w
protein intake. When dealing with spontaneous dietary intake,
without major side effects in Wistar male rats. Am J Physiol Regul n
the contribution of high-protein intake in lowering overweight l
Integr Comp Physio
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