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嗅沟脑膜瘤英文医学ppt课件
Olfactory Neuro Blastoma Surgical Approaches OGM usually require surgical treatment at time of diagnosis because of their size and associated mass effect Subfrontal approach Pterional approach Frontolateral approach Transsphenoidal Selection Criteria Tumor size Origin Placement according to midline The relationship of the anterior cerebral arteries Optic nerves Transsphenoidal Other therapies Radiation therapy is generally reserved for recurrences that are refractory to surgical resection Chemo therapy Targeted molecular therapy Complications CSF leak Meningitis Epilepsy Brain ischemia Hydrocephalus Worsening vision Prognosis OGM resection results were initially reported, mortality was from 17.3% to2.7% The recurrence rate of OGM ranges from 5 to 41% Factors Afecting Complete resection Brain retraction CSF leak Potential for vascular injury The size of the OGM Foster Kennedy syndrome Foster Kennedy syndrome (FKS) is a rare neurological sign first described in 1911 by Robert Foster Kennedy FK S is defined as one-sided optic atrophy with papilledema in the other eye but with the absence of a mass Presentation Optic atrophy in the ipsilateral eye Papilledema in the contralateral eye Central scotoma (loss of vision in the middle of the visual fields) in the ipsilateral eye Anosmia (loss of smell) ipsilaterally This syndrome is due to optic nerve compression, olfactory nerve compression, and increased intracranial pressure (ICP) (such as meningioma or Injury of anterior cranial Fossa, usually an OGM) There are other symptoms present in some cases such as : Nausea or vomiting Memory loss Emotional lability thank you Olfactory Groove Meningioma Introduction Meningiomas are believed to arise from the meningothelial cap cells that are normally distributed through the arachnoid trabeculations The greatest concentration of meningothelial cells is found in the arachnoid villi at the dural sinuses, cranial nerve foramina, middle cranial fossa, and the cribriform p
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