黑豆黑米茯苓配方的降脂作用与成分分析精选.pdfVIP

Pharmacy Information 药物资讯, 2017, 6(3), 72-77 Published Online July 2017 in Hans. /journal/pi /10.12677/pi.2017.63012 Hypolipidemic Effect of Black Bean Black Rice Poria Formula and Analysis on Its Components * Shengjun Pan , Huafeng Qiu, Lirong Li, Tieli Yang, Junxiang Song, Jianmin Ma Huanghuai University Research Center of Human Physiology, Zhumadian Henan th nd th Received: Jun. 19 , 2017; accepted: Jul. 2 , 2017; published: Jul. 17 , 2017 Abstract Objective: To observe the lipid-lowering effect of black beans and black rice poria formula and analysis its effective components. Methods: Components analysis was done by spectrophotometry. 30 cases of patients with high blood lipids, taking the lipid-lowering formula powder for 20 days, with the detection of blood lipid changes before and after lipid-lowering powder taking. 30 expe- rimental mouse, were randomly divided into control (C) group, high fat diet (HFD) group, high fat diet plus lipid-lowering powder (LLP) feeding group for a week, detecting the change of blood lipid. Result: The content of isoflavone was 3.8% (3.8% ± 0.5%) in the formula. In patients with hyperli- pidemia, the total effective rate of the lipid-lowering powder was 96.7%, triglyceride (TG), total cholesterol (TC) decreased significantly (p 0.05), low density lipoprotein (LDL) slightly decreased, high density lipoprotein (HDL) slightly elevated compared to that of the control. In mice experi- ments, TC of the high fat diet plus lipid-lowering food feeding group was significantly decreased (p 0.01) compared with high fat diet group. Conclusion: The black bean black rice poria powder formulation is rich in isoflavone, has lipid-lo