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临 床 综 述
Clinicalreview
食管的诊断和处理
DiagnosisandmanagementofBarrettSoesophagus
JanuszJankowski,一,HughBarr 一,KenWang ,BrendanDelaney
在西方成人,Barrett食管的患病率为 Gastrointestilml
OncdogyGroup,
本文要点 Universityof
2%,是仅次于结肠息肉的常见癌前病变之 Oxford,Oxford
一 2Centrefor
。 其中食管腺癌是最重要的并发症,终
Barrett食管多并发于慢性胃食管反流病 Di~stiveDisease
生风险在男性为5%,女性为3% 。诊断 B1izardInstitute,
Barrett食管的发病率呈上升趋势:在西方成 Queen
Barrett食管对患者来说其影响非常复杂, U vemiyt of
London.London
人 为2%
牵涉到预后不确定、担忧将来演变为癌症、 DigestiveDisease
Centre,Univemity
筛查需要重复内镜检查、药物和反复检查 ,Barrett食管相关食管腺癌的发病率亦呈上升 Hospitals。f
Leicester,Leicester
的费用等多方面问题 。目前正在开展关 趋势。在英国,尤其是苏格兰,食管腺癌的 CmnfieldHealth,
Cranfield
于高危人群筛查、化学预防、遗传分层以及 发病率高于全球任何地区 University,Cranfield
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