二叶式主动脉瓣疾病之之发病机理和治疗的新感悟（英文）幻灯片.pptVIP

Bicuspid Aortic Valve DiseaseNew Insights in Pathogenesis Treatment;Overview ;Background ;Etiology and Development of Congenital BAV;Bicuspid Aortic Valve (BAV) Morphology;Etiology and Mechanisms;Coronary Anomalies in BAV;Presentation of BAV Disease: Correlation With Patient Age;Anomalies Associated With BAV Disease;BAV and Aortic Dissection;;;The Role of Fibrillin-1 ;PNAS 1999; 96: 3891 ;Verma S, Circ Res 2001; 88(1): 37;Fibrillin-1 Deficient Mouse: Fibrillin-1 Deficient Tissues Release MMPs ;Matrix Disruption in BAV Patients;Objective ;Methods ;;Increased MMP-2 Activity;Increased MMP-2 A