High-throughput sequence alignment using Graphics Processing文档.pptVIP

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High-throughput sequence alignment using Graphics Processing文档.ppt

High-throughput sequence alignment using Graphics Processing文档

High-throughput sequence alignment using Graphics Processing Units Michael C Schatz, Cole Trapnell, Arthur L Delcher, Amitabh Varshney UMD Presented by Steve Rumble Motivation NGS technologies produce a ton of data AB SOLiD: 22e6 25-mers Others are even worse… How does 200e6 50-mers sound? Algorithms have been pushed hard, but typically assume same workstation CPU Wozniak and others showed S-W could be well-parallelised on special H/W. What of other algorithms/hardware? Motivation GPUs have recently evolved general purpose programmability (GPGPU) E.g.: nVidia 8800 GTX 16 multiprocessors 8

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