仔猪肠道疾病教学幻灯片.pptVIP

TGE Spreads Rapidly 传染胃肠炎传播快 Very short incubation period 潜伏期很短 Within 2-3 days majority of pigs on farm can be infected 2-3天内猪场内多数猪即被感染 Sources of Infection 传染胃肠炎传染源 Primarily infected shedding pigs 主要为受感染的排毒猪 People second most important 人是第二重要的传播因素 Starlings and other animals 椋鸟科鸟和其它动物 Diagnosis of TGE 传染胃肠炎诊断 Clinical signs 临床症状 Necropsy 病理剖检 Diagnostic Laboratory 实验室诊断 histological confirmation 病史确认 positive FA test 荧光抗体阳性检测 Treatment of TGE 传染胃肠炎治疗 Keep warm 保暖 Antibiotics to control secondary bacteria 应用抗生素防止继发感染 Wean pigs early 早期断奶 Young pigs rarely survive despite treatment efforts 尽管进行治疗，年龄小的猪仍然很少存活。 Enteric Diseases of Young Pigs仔猪肠道疾病 Diarrhea remains one of the leading causes of neonatal mortality in swine 下痢一直是新生仔猪死亡的主要原因 Definition of Diarrhea下痢的定义 Excess water in feces relative to dry matter.粪中含水量过大 Normally, much of the fluid is absorbed in the small intestine before it exits the ileum 通常，大部分水都在进入回肠之间就在小肠中被吸收了 Colon serves to conserve water and electrolytes结肠只起吸收水和电解质的作用 Mechanisms of Diarrhea下痢的机理 Secretory Diarrhea分泌性下痢 Result of the effect of enterotoxins secreted by bacteria and some viruses细菌和其它病毒分泌的肠毒素造成的结果 Alteration in secretion of electrolytes, water, and bicarbonate: gradient pulls water into lumen电解质、水和碳酸氢钠的分泌发生改变：使水进入肠腔 Absorption continues: Chyle in lymphatics Mechanisms of Diarrhea下痢的机理 Malabsorptive Diarrhea吸收不良性下痢 Reduction in surface area of intestine肠粘膜表面积减少 Loss of absorptive capacity吸收能力减弱 Villous atrophy绒毛萎缩 Chyle absent in lymphatics淋巴乳糜缺乏 Undigested ingesta ferments未消化的食糜发酵 Mechanisms of Diarrhea下痢的机理 Effusive Diarrhea渗漏性下痢 Result of severe damage to mucosa粘膜严重受损的结果 Necrotoxins produced by bacteria细菌产生的坏死毒素 Leakage of serum proteins and water due to vascular damage血管受损导致血清蛋白质和水漏出 Loss of absorptive capacity吸收能力减弱 Arriving at a Diagnosis诊断 History病史 Age of onset发病年龄 Vaccination history免疫接种历史 Sudden death vs. protracted diarrhea猝死和长期下痢 Arriving at a Diagn