The non random location of human oncogenes and tumour…人类致癌基因和肿瘤的非随机位置.pdfVIP

CARYOLOGIA Vol. 58, no. 1: 1-14, 2005 The non-random location of human oncogenes and tumour sup- pressor genes Lima-De-Faria Antonio and Bengt Widegren* Department of Cell and Organism Biology, Genetics Building, Lund University, So¨ lvegatan 29, 223 62 Lund, Sweden Abstract — We have analysed 994 sites for oncogenes and tumour suppressor genes located within human chromo- some bands. The data presented disclose that: 1) These cancer genes build ridges as well as hot spots, which are not r