genome基因表达调控的基本知识.ppt

glucose (+), cAMP↓ CAP Positive Regulation (Ⅱ) Transcription 0 + DNA P O Z Y A CAP Coordinance Regulation Lactose ( - ) Lactose ( + ) Glucose (-) cAMP↑ Glucose (+) cAMP↓ mRNA mRNA mRNA O O mRNA O RNA Pol The Mechanism of Lac Operon Regulation Lac ( - ) Lac ( + ) Glucose ( + ) Glucose ( - ) Lac gene transcription Inhibits Induces No enhances Enhances + - Lac ( + ) G ( - ) Lac ( - ) G ( + ) Lac ( + ) G ( + ) Lac ( - ) G ( - ) ? ? Significance of The Lac Operon Regulation ※ The lac operon model is common. ※ The repressor and its negative regulation are universal, to