An FPGA-based open platform for ultrasound biomicroscopy推荐.pdfVIP

1432 I E E E T r a n s ac T I o n s o n U lT r a s o n I c s , F E r ro E l E c T r I c s , a n d F r E q U E n c y c o n T ro l , vol. 59, no. 7, j U ly 2012 An FPGA-Based Open Platform for Ultrasound Biomicroscopy Weibao qiu, yanyan yu, Fu Keung Tsang, and lei sun Abstract—Ultrasound biomicroscopy (UBM) has been ex- clinically used for ophthalmology [8], dermatology [9], and tensively applied to preclinical studies in small animal models. intravascular diseases [10]. Preclinical small animal model Individual animal study is unique and requires different utiliza- research has also been significantly propelled by UBM, for tion of the UBM system to accommodate different transducer characteristics, data acquisition strategies, signal processing, example, in malignant tumor diagnosis [11], [12], cardiac and image reconstruction methods. There is a demand for a diseases [13], [14], and embryonic developmental biology flexible and open UBM platform to allow users to customize [15], [16]. recently, UBM has been combined with optical the system for various studies and have full access to experi- methods such as ocT or fluorescence spectroscopy as a mental data. This paper presents the development of an open dual-modality imaging technique and has demonstrated UBM platform (center frequency 20 to 80 MHz) for various preclinical studies. The platform design was based on a field- great potential in biomedical studies [17]–[19]. other ad- programmable gate array (FPGA) embedded in a printed cir-