抗生素课件课件(英文精品) Drug Action in the Cell.pptVIP

Predicting Efflux of Antibiotics by AcrAB-TolC Pumps;Efflux Pumps;AcrB;Why Study Efflux Pumps? ;Drug Action in the Cell;Research Questions;Experimental Data;Calculation of Molecular Parameters;Partial Least Squares (PLS);First Model for Efflux;Linear vs. Quadratic Regression;Second Model for Efflux;Further Validation;Training Set/Test Set Validation;Correct Predictions of the Models;Comprehensive Model for Efflux;Summary;Conclusions;Acknowledgements