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How many people die from the flu in a “normal” year in the U.S.? ~36,000 About 90% are over 65 years old /flu/about/disease/index.htm Spanish flu of 1918-1919 Killed between 20-50 million people worldwide; 675,000 in the U.S.(2.5%-5% of world population) Infected 1/5 to 1/4 of world population Was most lethal to people 20-40 years old /uda//uda/ Spanish flu of 1918-1919 People on their way to work suddenly developing the flu and dying within hours (Henig).One physician writes that patients with seemingly ordinary influenza would rapidly develop the most viscous type of pneumonia that has ever been seen and later when cyanosis appeared in the patients, it is simply a struggle for air until they suffocate, (Grist, 1979).Another physician recalls that the influenza patients died struggling to clear their airways of a blood-tinged froth that sometimes gushed from their nose and mouth, (Starr, 1976). /uda//uda/ The high fatality rate from the Spanish flu was probably due to an immune system over-reaction HIV, a retrovirus, infects Helper T-cells CB19.8 HIV reproduction CB19.8 Reverse Transcriptase: RNA to DNA HIV has both a lytic and lysogenic cycle CB19.8 /talks/lang/eng/nathan_wolfe_hunts_for_the_next_aids.html Where did HIV come from, and where is the next HIVesque virus? Ebola E. coli Fungus from soil Phage virus This week: Microorganisms and Pathogens Ebola E. coli Fungus from soil Phage virus This week: Microorganisms and Pathogens CB 26.21 Bacteria Archae Fungi Animals Protists Plants CB 1.15 CB 6.6 Prokaryotic cells: simple cells, no internal membranes CB 27.2 Bacteria can be classified by cell shape Different species of bacteria use different nutrition sources lag exponential stationary Bacteria can divide rapidly CB 53.12 CB 53.22 Human Population Growth CB 27.19 Some bacteria help provide nutrients for plants The nitrogen cycle Nitrogen as part of amino acids N N N The nitrogen cycle What do bacteria do?from a human perspective Good Decay dead
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