(精编)【医学英文课件】 SOME RECENT ADVANCES IN RHEUMATOLOGY教学课件.pptVIP

Dosing Regimens of Biologics KINASE TARGETS IN DEVELOPMENT Kinases such as Janus kinase 3 are intracellular molecules that play a pivotal role in signal transduction of interleukins. Spleen tyrosine kinase could serve as a novel and promising target for immune intervention in rheumatic diseases. Tofacitinib – A Janus Kinase inhibitor that is currently available for use in patients who have had an inadequate response to or intolerance of methotrexate in RA RHEUMATOID ARTHRITIS: treat to target Grading Disease Severity Mildly active disease Fewer than five inflamed joints Mildly elevated or n