(精编)ANTIMICROBIAL DRUGS教学课件.pptVIP

ANTIMICROBIAL DRUGS;MECHANISMS OF ACTION OF ANTIBACTERIAL DRUGS;MECHANISMS OF ACTION OF ANTIBACTERIAL DRUGS;MECHANISMS OF ACTION OF ANTIBACTERIAL DRUGS;Vancomycin Inhibits formation of glycan chains Inhibits formation of peptidoglycans and cell wall construction Does not cross lipid membrane of Gram - Gram - organisms innately resistant Important in treating infections caused by penicillin resistant Gram + organisms Must be given intravenously due to poor absorption from intestinal tract Acquired resistance most often due to alterations in side chain of NAM molecule Prevents binding of vancomy