(精编)Immunology SimplifiedAutoimmune disease Fall 2016教学课件.ppt

SEGS…margination, pavementing, migration, engulfment, and degranulation Margination, pavementing, migration and engulfment and degranulation (release of preformed granules) Marginating segs (measured by WBC count) Pavementing segs (stuck to walls) Yum Prednisone is a potent anti-inflammatory drug Prednisone is a corticosteroid; It inhibits migration, engulfment and degranulation of the neutrophil; hence, its potent anti-inflammatory properties Why do we use Prednisone with autoimmune disease? For two reasons: 1) To inhibit the damage caused by one’s own neutrophils attacking various tissues 2