医疗影像处理在诊断上之应用 高大资工.ppt

Background Region Contours within a sequence of frames Result Tab 4.1 心室功能量測參數 Virtual colonscopy-Browsing or navigation within a colon Helical CT –patients injected contrast medium Re-sampling—Voxel-based Interpolation Automatic segmentation (seed) threshloding Determination of the skeleton of the colon Connected-Component Labeling Surface rendering and volume rendering Extraction of suspicious sub-volumes for diagnosis Automatic segmentation Determination of the skeleton of the colon Display and measurement Bone tumor segmentation with MRI and virtual display—Contrast medium Otsu thresholding Region growing Tri-linear interpolation Morphological post-processing Surface rendering Measurement Histogram of T1 weighted and T2 weighted (a) 0度 (b) 45度 (a) 0度 (b) 45度 Classification of Breast Carcinoma 正常 異常 系統判斷為正常 12 6 系統判斷為異常 1 11 準確性 敏感度 有效性 76.67% 64.71% 92.31% Requirements for medical image processing system in clinical diagnosis Automatic and less human interaction Qualitative and quantitative measurements Stable and reliable (experiments with much more cases) Performance evaluation True positive, true negative, false positive, false negative Accuracy, sensitivity, and specificity Receiving operating characteristic curve (An index for evaluating the effectiveness of classification Optimal classification threshold Area under ROC approach 1 – better classification ROC curve Analyses of prognosis on breast cancer for a stained tissue Microscopy with different resolution (400 or 100) for a stained tissue Fluorescent microscopy in detecting the number of chromosome Immunohistochemistry(IHC) Preliminaries or problems ? Blurring often caused by patient motion or respiration Clinical opinion or idea obtained from an experienced surgeon Non-absolute answers at some specific conditions Trade-off between complexity and performance Large variations for different image modality Automation is necessary so as to h