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Autistic Spectrum Disorders AKA PDD - University of Florida自闭症又名PDD -佛罗里达大学.ppt
* * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * Pharmacological Approaches Research with some drugs have shown them to be more effective. For example, one drug (Haloperidol), which has been used with adult schizophrenics and some other clinical groups, has been shown to improve the learning ability of autistic children and make them more responsive to special education and behavior modification An especially noteworthy aspect of this treatment is that therapeutic effects were obtained with lower doses that do not seem to produce serious side effects Additional Drug Treatments A recent NIMH Multisite study (2005) has found newer, atypical antipsychotic medications such as Risperdal? to be useful in the treatment of autism. This medication, has been found to not only decrease aggression but also reduced repetitive behaviors and increase social interaction - all with limited side effects. The two-part study found that discontinuation after six months prompted rapid return of the problem behaviors in most cases. Other drugs such as the SSRI’s may also be useful in reducing repetitive behavior social avoidance in individuals with autism. These seem to be more effective with adolescents with autism as opposed to younger children. The use of other atypical antipsychotic drugs (e.g. Abilify) is also being researched as well. Multimodal Treatments While behavior therapy and drug treatments have both shown some promise in treating autism, there is research evidence to suggest that treatment should not be an either/or proposition. For example, early research by Campbell, et al (1987) focused on the efficacy of a combination of Haloperidol and behavior modification in the treatment of 40 autistic children. The results of this study suggested that while haloperidol alone was effective in reducing stereotyped behavior and withdrawal, a combination of drug treatment and behavior therapy was su
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