Large Soluble Oligomers of Amyloid β-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate（大的水溶性oligomersβ淀粉样蛋白是阿尔茨海默氏症的大脑中的神经活性远低于比smaller oligomers这对他们dissoci.pdfVIP

152 • The Journal of Neuroscience, January 4, 2017 • 37(1):152–163 Neurobiology of Disease Large Soluble Oligomers of Amyloid -Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate Ting Yang, Shaomin Li, X Huixin Xu, Dominic M. Walsh, and Dennis J. Selkoe Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115 Soluble oligomers of amyloid -protein (oA) isolated from the brains of Alzheimer’s disease (AD) patients have been shown experi- men