槐米金针花浸膏的抗氧化活性及其对卷烟危害性的影响-烟草科技.PDF

/TobaccoScienceTechnology /TobaccoChemistry 2009 7 ( 264 ) 、 1 1 2 , 　 , 1.广东中烟工业有限责任公司技术中心, 广州市天河区林和西横路 203 号　510610 2.华南理工大学 工与食品学院, 广州市五山路 381 号　510640 :酶制剂;中草药浸膏;卷烟;急性毒性试验 :为降低吸烟的危害, 进行了槐米浸膏和金针花浸膏的抗氧化活性试验, 槐米浸膏、金针花浸膏、纤 维素酶和中性蛋白酶混合物添加的卷烟烟气对 SPF小鼠和 Wistar大鼠的急性毒性致死试验。结果表 - 明:①槐米浸膏和金针花浸膏具有较强的清除 ·OH和 ·O 自由基的能力;②与对照组相比, 抽吸含槐 2 米浸膏、金针花浸膏、纤维素酶和中性蛋白酶混合物卷烟的大鼠存活时间明显延长, 其心肝肺组织损伤 程度明显较 。 :TS416, TS264.3　:B　:1002 -0861 (2009 )07-00 38-05 AntioxidantActivityofFlosSophoraeimmaturusandDay- lilyConcretesandTheirInfluenceson HealthRiskofCigarette JINJIN-SONG(1), WENJUN(1), andLIUTONG-XUN(2 ) 1.TechnologyCente,rGuangdongBranchofChinaTobaccoIndustryCorporation, Guangzhou510 610, China 2.CollegeofLightandFoodEngineering, SouthChinaUniversityofTechnology, Guangzhou5 10640, China Keyword:sEnzymaticagen;tChineseherbconcrete;Cigarette;Acutetoxicitytest Abstrac:tForreducingthehealthriskofsmoking, theantioxidantactivityofamixtureofFlosSophorae mimaturusconcreteandday-lilyconcretewasdetermined, theacutetoxicaldeathexpermientsofSPFmouse andWistarratsexposedtothemainstream smokeofcigarettesaddedwithamixtureofFlosSophorae mimaturusconcret,eday-lilyconcret,e cellulaseandneutralproteinasewereconducted, andthesectionsof hear,tlungandliverfromdeadratswerehistopathologicallyexaminedaswel.lTheresultsshowedtha:t1)the - twoconcreteswerestronginscavengingthefreeradical,s·OHand·O, and2 )comparingwiththe 2 contro,ltheratsexposedtomainstreamsmokeofcigarettespikedwiththemixturesurvivedsignificantlylonger andtheirinternalorganswereobviouslylessinjured. 　　 [1-10][ 10 -12] 。, , , [8] 。,