香砂脘痛胶囊质量的研究.pdfVIP

Pharmacy Information 药物资讯, 2017, 6(2), 25-30 Published Online May 2017 in Hans. /journal/pi /10.12677/pi.2017.62005 Quality Standard of Xiangshawantong Capsule 1 2 Zhenjie Xin , Qiuhong Rao 1 Luoding Hospital of Traditional Chinese Medicine, Luoding Guangdong 2 The First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou Guangdong th th rd Received: Apr. 16 , 2017; accepted: Apr. 30 , 2017; published: May 3 , 2017 Abstract Objective: To establish the quality standard Xiangshawantong Capsule. Methods: Thin-Layer chro- matography (TLC) was employed for the qualitative determination of Chuanxiong Rhizoma, Ange- licae Sinensis Radix and Paeoniae Radix Rubra High performance liquid chromatography (HPLC) was applied for the determination of Vitexin in Xiangshawantong Capsule. Results: The characte- ristic by TLC was obvious and highly specific. The Linear range of Vitexin ranged from 0.0576 - 0.2880 μg (r = 0.9998). The average recovery was 99.73% (RSD = 2.1%, n = 6) respectively. Con- clusion: The established standard can be used for the quality control of Xiangshawantong Cap- sule. Keywords Xiangshawantong Capsule, Quality, TLC, HPLC 香砂脘痛胶囊质量研究 1 2 辛振杰 ，饶秋红 1罗定市中医院，广东 罗定 2广州中医药大学第一临床医学院，广东 广州 收稿日期：2017年4月16 日；录用日期：2017年4月30 日；发布日期：2017年5月3 日 摘 要 目的：探讨建立控制香砂脘痛胶囊质量的方法。方法：采用薄层色谱法(TLC)对川芎、当归和赤芍药材 文章引用: 辛振杰, 饶秋红. 香砂脘痛胶囊质量研究[J]. 药物资讯, 2017, 6(2): 25-30. /10.12677/pi.2017.62005 辛振杰，饶秋红 进行定性鉴别，采用高效液相色谱法(HPLC)对牡荆苷进行含量测定。结果：TLC特征斑点明显清晰、专 属性强。牡荆苷在0.0576~0.2880 μg (r = 0.9998) 间具有良好的线性关系，平均回收率分别为99.73% (RSD = 1.5%, n = 6) 。结论：所建标准