心血管支架材料生物力学及生物相容性特征精选.doc

心血管支架材料生物力学及生物相容性特征 中国组织工程研究与临床康复笫J2眷笫J3期2008—03—25出版 JournalofClinicalRehabilitativellssueEngineeringResearchMarch25,2008Vo1.12,No.13 心血管支架材料生物力学及生物相容性特征★ 曾伟杰,凌友,支晓兴 Biomechanicsandbiocompafibilitycharacteristicsofcardiovascularstents ZengWei-jie,LingYou,ZhiXiao-xing Abstract AIM:Toanalyzethecharacteristicsofcardiovascularstentsandresearchstatusofbiomechanicsandbiocompatibilityafter.Departmentof implantation.Cardiovascular METHODS:Acomputer.basedonlinesearchofPubmedandChineseJournalFul1.textDatabasewasundertakentoidenfifyrelated叫mc,. articles.Afterthefirsttria1.articlesaboutca/diovasculardisease,coronaryartery.scaffoldmaterialandbiocompatibilitywere: selectedandthefull—textwerelookedup.Onlyarticlescorrelatedwithcardiovascularstentandthebiocompatibilitywereincluded. 510318,Guangdong andthosepublishedinrecent5yearsorinauthoritativejournalswerepreferred.RepetitivestudiesandMetaanalysiswereexcluded.vince,China; RESULTS:Q-)Cardiovascularstentmaterialsincludebaremetalstents.drug-elutingstentsandbiodegradablescaffolds. Theo儿.:improvementofbiocompatibilityandbiomechanicsofstentmaterialsis-i- m -, por -- ta -o nt - . ~Biocompatibilityofcardiovascularstentsisa誊篓rirI complexprocess.Bloodcompatibilityandtissuecompatibilityaretwobasicitemstoassessbiocompatibility.⑨Finiteelements0utllChina analysisthatiSusedtoevaluatethemechanicalcharacteristicsofscaffoldiShelpfulforoptimaldesignoffuturestents.Universityof CONCLUSION:Biocompatibilityofcardiovascularstentshasnotbeenyetcompletelysolved.Idealcardiovascularstentsneedtohn. befunI1erdevelopedandstudied.. G U uangd.ng ZengWJ,LingY.ZhiXX.Biomechanicsandbiocompatibilitycharacteristicsofcardiovascularstems.ZhongguoZuzhiGongcheng YanjiuyuLinchuangKangfu2008;12(13):2531—2534(China)[/zglckf/ejoumal/upfiles/08—13/13k一2531(ps).pdq 摘要 目的:分析心血管支架材料的特点和植入后生物力学与生物相容性的研究现状. 方法:检索Pubmed数据库和中国期刊全文数据库文献.然后对资料进行初审.选取包括心血管,冠状动脉,支架材料,生 物相容性的文献开始查找原文,并查看文献后的引文文献.纳入标准:文章所述的内容为心血管支架材料及其生物相容性 的研究:以近5年且发表在较权威的杂志者优先.排除标准:重复的研究或Meta分析类文章. 结果:①心血管支架中不论是金属裸支架,药物涂