The different outcomes between breast-conserving surgery and mastectomy in triple-negative breast cancer a population-ba.手术与乳房之间的不同结果三阴性乳腺癌以人群为基础的研究从SE_推荐.pdfVIP

/oncotarget/ Oncotarget, Advance Publications 2016 The different outcomes between breast-conserving surgery and mastectomy in triple-negative breast cancer: a population-based study from the SEER 18 database 1,* 1,* 1,* 1 1 Qing-Xia Chen , Xiao-Xiao Wang , Pei-Yang Lin , Jie Zhang , Jun-Jing Li , 1 2 Chuan-Gui Song , Zhi-Ming Shao 1 Department of Breast Surgery, Affiliated Union Hospital, Fujian Medical University, Fuzhou, China 2 Department of Breast Surgery, Key Laboratory of Breast Cancer, Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University, Shanghai, China * These authors contributed equally to this work Correspondence to: Chuan-Gui Song, email: songchuangui@ Keywords: breast-conserving surgery, mastectomy, triple-negative breast cancer, breast cancer-specific survival, overall survival Received: August 12, 2016 Accepted: December 07, 2016 Published: December 16, 2016 ABSTRACT Breast-conserving surgery (BCS) including radiotherapy (RT) has been demonstrated to provide at least equivalent prognosis to mastectomy in early-stage breast cancer. However, studies on triple-negative breast cancer (TNBC) patients are relatively scarce. The current population-based study aimed to investigate the distinct outcomes between BCS+RT and mastectomy in patients with TNBC. Utilizing the Surveillance, Epidemiology, and End Results (SEER) database, we enrolled 11,514 female TNBC cases diagnosed during the years 2010–2013. Those patients were subdi