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* Three randomised studies of varying quality have shown that there is no advantage to immediate treatment in patients with advanced stage asymptomatic FL compared with a watchful waiting approach in terms of 总生存期, so_ 1. Patients who undergo observation do not have an increased risk of high grade transformation (Brice et al, 1997; Horning et al, 1984; Al-Tourah et al, 2008) compared to those who start treatment immediately. * * Three randomised studies of varying quality have shown that there is no advantage to immediate treatment in patients with advanced stage asymptomatic FL compared with a watchful waiting approach in terms of 总生存期, so_ 1. Patients who undergo observation do not have an increased risk of high grade transformation (Brice et al, 1997; Horning et al, 1984; Al-Tourah et al, 2008) compared to those who start treatment immediately. 致谢 优势能力网络 恶性淋巴瘤 患者 临床研究 www.lymphome.de 大学医院 初级保健医生 社区医院 临床实践中的肿瘤科医生 * Three randomised studies of varying quality have shown that there is no advantage to immediate treatment in patients with advanced stage asymptomatic FL compared with a watchful waiting approach in terms of 总生存期, so_ 1. Patients who undergo observation do not have an increased risk of high grade transformation (Brice et al, 1997; Horning et al, 1984; Al-Tourah et al, 2008) compared to those who start treatment immediately. * * * Three randomised studies of varying quality have shown that there is no advantage to immediate treatment in patients with advanced stage asymptomatic FL compared with a watchful waiting approach in terms of 总生存期, so_ 1. Patients who undergo observation do not have an increased risk of high grade transformation (Brice et al, 1997; Horning et al, 1984; Al-Tourah et al, 2008) compared to those who start treatment immediately. * Three randomised studies of varying quality have shown that there is no advantage to immediate treatment in patients with advanced stage asymptomatic FL compared with a watchful waiting
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