卵巢恶性肿瘤胃肠道转移的手术治疗(附131例临床分析).docVIP

卵巢恶性肿瘤胃肠道转移的手术治疗(附131例临床分析) 中华肿瘤杂志 1999年第2期第0卷 临床应用 作者：彭芝兰　潘小玲　刘辉　王红静　张崇淑　黎培毅　杨延林　王小莉 单位：610041 成都，华西医科大学附属第二医院妇产科 　　关键词： 卵巢肿瘤；胃肠肿瘤/继发性；胃肠肿瘤/外科学；手术后并发症 　　【摘要】　目的　总结分析卵巢恶性肿瘤胃肠道转移手术及并发症特点，探讨其治疗价值及可行性。方法　回顾性分析131例卵巢恶性肿瘤胃肠转移（转移瘤直径≥2 cm）行手术治疗患者的临床资料。统计数据采用计算机软件处理。结果　卵巢恶性肿瘤胃肠转移占同期收治原发性卵巢恶性肿瘤的28.9%，Ⅲ、Ⅳ期占93.9%。治疗方式为手术加化疗，58.9%行单纯肠壁病灶切除及修补，41.1%行部分肠切除术。术后并发症发生率为26.9%，术后2年及5年生存率分别为79.7%和42.5%。结论晚期卵巢恶性肿瘤胃肠转移实施肠道手术是必要及可行的，成功的缩瘤术及术后及时足量的化疗是改善患者预后的关键。 　　Surgical treatment of ovarian malignant tumors metastasized to the gastro-intestinal tract: a report of 131 cases　　PENG Zhilan，PAN Xiaoling，LIU Hui，et al. Department of Obstetrics and Gynecology, Second Affiliated Hospital, West china University of Medical Sciences, Chengdu 610041 　　【Abstract】　Objective　To investigate the value and feasibility of surgical excision of gastro-intestinal metastatic tumors in patients with ovarian malignancy.Methods　The surgical and clinical data were retrospectively reviewed in 131 cases of ovarian malignant tumor with surgically excised gastrointestinal metastasis (≥2 cm in diameter).Results　Ovarian malignant tumor with gastro-intestinal metastasis accounted for 28.9% of the patients with primary ovarian malignancies in the same time period. Of the 131 cases, 126(93.9%) were in stage III and IV. The treatment was surgical excision combined with chemotherapy. Of the 141 operations, 83(58.9%) were done by stripping of tumors on the gastro-intestinal wall and repair, 31(22.0%) received resection of the involved segment of the bowel with anastomosis, 27(19.2%) with colostomies. Postoperative complications occurred in 26.9% of the operated patients. The overall 2- and 5-year survival rate was 79.7% and 42.5%, respectively.Conclusion　Surgical excision of gastro-intestinal tumors metastasized from primary ovarion malignancies is feasible to achieve cytoreduction. Prognosis can be improved when combined with chemotherapy. 　　【Subject words】　Ovarian neoplasms　　Gastrointestinal tract neoplasms/secondary　　Gast