Programming_and_database_management_for_bioinformatics：生物信息学编程和数据库管理.pdf

omicsuvic.net COURSES IN BIOINFORMATICS AND OMICS DATA ANALYSIS Programming and database management for bioinformatics The aim of this course is to provide some important programming and database management skills that are essential for bioinformatics: using Linux operating system, managing databases, programming in Python, using and writing statistical functions in R. Program:  Linux  Programming Languages for Bioinformatics: Python  Database Management  R and Bioconductor Lecturers and trainers: Alfons Nonell, Mindthe Byte Víctor Urrea, Systems Biology Dept, EPS, Uvic 1 Statistical and data-mining methods for omics data analysis The aim of this course is to introduce the most important statistical and data mining methods for bioinformatics and omics data analysis. The course combines lectures with hands-on sessions using R for illustration of the different methodologies. Program: 1. Exploratory data analysis – Descriptive statistics a. Usual data structures b. Gene expression data structure c. Type of variables d. SNP and gene expression data e. Univariate data analysis i. Frequency tables ii. Summary statistics iii. Plots f. Bivariate data analysis i. Measures of correlation ii. Contingency tables, measures of associations, measures of risk (RR and OR) 2. Important distributions a. Binomial b. Normal c. T (Student dist.) d. Chi-squared