绝经后子宫肌瘤76例临床病理分析.docVIP

绝经后子宫肌瘤76例临床病理分析 【关键词】 ,绝经后；子宫肌瘤；临床病理特征 【摘要】 目的 研究绝经后子宫肌瘤患者的临床病理学特征，探讨合理的治疗原则。方法 对我院2000年1月至2005年6月收治的绝经后子宫肌瘤患者76例与未绝经子宫肌瘤患者785例的临床病理学资料进行对照性研究。结果 子宫出血是绝经后子宫肌瘤患者最常见的临床表现，下腹疼痛者绝经组高于未绝经组（P＜0.05），绝经组术后病率明显高于未绝经组（P＜0.01），绝经后子宫肌瘤合并变性、恶性肿瘤的比例高于绝经前（P＜0.05）。结论 绝经后子宫肌瘤具有其独特的临床病理特征，应适当放宽手术指征，采取个体化治疗，提高绝经后子宫肌瘤的整体治疗水平。 【关键词】 绝经后；子宫肌瘤；临床病理特征 Clinical pathological analysis for 76 cases of postmenopausal uterine leiomyoma HOU Zhimin.Department of Obstetric and Gynecology,Union Medical Center,Tianjin 300120 【Abstract】 Objective To investigate the clinical pathological characteristics of uterine leiomyoma in postmenopausal women and to explore the reasonable therapeutic principle.Methods The clinical pathological records of 76 patients with postmenopausal uterine leiomyomas and 785 patients with premenopausal uterine leiomyomas who were treated in our hospital from January 2000 to June 2005 were retrospectively analyzed.Results According to the analytic data,the most common symptom of patients with postmenopausal uterine leiomyomas was postmenopausal bleeding （53.95%）,abdomen pain was more common in postmenopause group than that in premenopause group （P＜0.05）,the incidence of degeneration in leiomyoma and malignant tumor was increased in patients with postmenopausal bleeding （P＜0.05）.Conclusion The clinical pathological characteristics of postmenopausal uterine leiomyomas are different from those of the premenopausal uterine leiomyoma，and rational individual treatment can improve the outcomes of patients with postmenopausal uterine leiomyoma. 【Key words】 postmenopausal；uterine leiomyoma；clinical pathological characteristics 子宫肌瘤是常见的妇科良性肿瘤，多见于生育期妇女，一般认为，绝经后妇女由于卵巢功能的衰退而出现雌、孕激素水平降低和缺乏，肌瘤不再增长甚至萎缩，据此临床医师常对围绝经期的子宫肌瘤患者采取期待疗法；但同时也发现，尚有一部分绝经后患者因出现阴道出血、压迫症状、腹痛等表现而进行手术治疗。本研究对2000年1月至2005年6月在我院妇科住院手术治疗并经病理证实为子宫肌瘤的绝经后患者共76例的临床病理资料进行回顾性分析,以探讨绝经后子宫肌瘤患者的临床病理学特点，指导绝经后子宫肌瘤的诊断和个体化治疗。 1 临床资料 11 一般资料 2000年1月至2005年6月我院妇科病房共收治子宫肌瘤患者861例，其中绝经后患者（绝经组）76例占8.83%，未绝经子宫肌瘤患者（未绝经组）785例占91.17%；对两组患者的临床和病理资料