胎膜促肾上腺素皮质激素释放激素受体表达与社会因素剖宫产的相关性.docVIP

胎膜促肾上腺素皮质激素释放激素受体表达与社会因素剖宫产的相关性 【关键词】胎膜 P style=TEXT-INDENT: 24px【摘要】 目的 探讨胎膜促肾上腺素皮质激素释放激素受体（CRHR1）mRNA表达与社会因素剖宫产的相关性。方法 采用半定量逆转录聚合酶链反应（RT-PCR）检测10例顺产、20例社会因素剖宫产产妇的胎膜上CRHR1mRNA的表达，分析其表达差异与社会因素剖宫产的相关性。结果 CRHR1mRNA在顺产产妇的胎膜中的表达显著高于社会因素剖宫产产妇的胎膜（P0.05）。结论 社会因素剖宫产产妇胎膜中CRHR1mRNA表达较顺产者表达下调，提示CRHR1基因表达差异与社会因素剖宫产可能相关。P style=TEXT-INDENT: 24px关键词 分娩方式 促肾上腺皮质激素释放激素受体 基因 聚合酶链反应 胎膜P style=TEXT-INDENT: 24px align=centerExpression of corticotropin-releasing hormone receptor subtype1mRNA inP style=TEXT-INDENT: 24px align=centerfetal membrane and the correlation to term elective cesarean sectionP style=TEXT-INDENT: 24px align=centeron psychological factors Sui Hongying，P style=TEXT-INDENT: 24px align=centerZhu Fufan，Tao Guangshi，et al.P style=TEXT-INDENT: 24px align=centerDepartment of Obstetrics and Gynecology，The Second Affiliated Hospital of Xiang Ya Medical College of Central South University，Changsha410011.P style=TEXT-INDENT: 24px【Abstract】 Objective To investigate the expression of corticotropin-releasing hormone receptor subtype1（CRHR1）mRNA in fetal membrane whether related to the term elective cesarean section on psychological factors.Methods We detected CRHR1mRNA in fetal membrane of10vaginal delivery，20elective cesarean section on psyˉchological factors in late pregnant women by semi-quantity reverse transcrip tion-polymerase chain reaction（RT-PCR）.Analyzed the relativity of CRHR1mRNA different expression and term elective cesarean section on psychologiˉcal factors .Results CRHR1mRNA expression in fetal membrane of vaginal delivery was higher than that of term elective cesarean section on psychological factors in late pregnant women（P0.05）.Conclusion Expression of CRHR1mRNA in fetal membrane of late pregnant women is evidently decreased in term elective cesarean section on psychological factors.It is suggested that CRHR1expression may relate to term elective cesarean section on psychologiˉcal factors.P style=TEXT-INDENT: 24pxKey words delivery mode corticotropin-releasing