ch2核酸的结构与功能2h.pptVIP

* * The forces stabilizing the DNA double helix can be overcome by heating the DNA in solution or by treating it with very high or very low pH (low pH will also damage the DNA, whereas high pH will simply separate the polynucleotide chains). When the strands of DNA separate, the DNA is said to be denatured (when high temperature is used to denature DNA, the DNA is said to be melted). Because some of the forces stabilizing the DNA double helix are contributed by base pairing interactions, and because A-T base pairs have only two hydrogen bonds in contrast to G-C base pairs which have three