牵引成骨区牙移动生物学行为的实验研究论文论文.docVIP

上海交通大学 2005 级口腔临床医学硕士学位论文 4 牵引成骨后一个月组符合传统正畸牙移动规律，加载 150g 力实验牙远中移动速度 平均为 0.4675±0.0213mm/w，加载 30g 力实验牙移动速度平均为 0.48± 0.0429mm/w，两组力值均未见明显牙根吸收。 5 对照组符合传统正畸牙移动规律，加载 150g 力实验牙移动速度平均为 0.3393± 0.028mm/w，加载 30g 力第三前磨牙远中移动速度平均为 0.3025±0.0267mm/w， 两组力值均未见明显牙根吸收。 6 牵引成骨后即刻组，实验牙远移速度快于一个月后组和对照组（P＜0.05）。加 载 150 力牙根表面可见较大范围的吸收陷窝，深度达牙本质浅层；加载 30g 力牙根表 面可见小的吸收陷窝，深度局限于牙骨质层。 结论： 1 成功建立 beagle 犬牙移动进入下颌骨牵引成骨区的实验动物模型。 2 即刻组实验牙平均移动速度达到约 1 mm/w，相当于一个月后组的 2 倍，相当于对 照组的 3－4 倍。 3 对照组和一个月后组牙移动规律符合传统正畸牙移动规律，未见明显牙根吸收，增 加实验牙矫治力并不能加快实验牙的移动速度。 4 即刻组牙移动规律不同于传统正畸牙移动规律，未见迟滞期，增加实验牙矫治力值 并不能加快实验牙的移动速度且可能造成明显的牙根吸收，提倡早期轻力移动牙 齿进入牵引成骨区。 5 牙周组织的改建能力能够适应牵引成骨新骨区实验牙的快速移动。 关键词：牵引成骨 牙移动 骨改建 动物模型 组织学 -2- 上海交通大学 2005 级口腔临床医学硕士学位论文 The experiment on biological behavior of orthodontic tooth movement into newly distracted bone Postgraduate: Lou xintian  Superviser:  Fang bing  Abstract Aim. The present study is to establishing an animal model in dog for experimental orthodontic tooth movement into newly distracted bone after mandibular distraction osteogenesis. To select a clinical optimal time and optimal force of tooth movement into newly distracted bone. To investigate the biological behaviour of the experimental tooth. Methology. Twelve 15-month-old male beagles, weighing 12-14kg were selected as subjects in this study. Eight beagles underwent 10 mm of bilateral mandibular distraction osteogenesis. After surgery randomly grouped into 4 groups. After 0-week and 4-week consolidation periods, the third premolars were moved distally into the regenerate bone with 30g or 150g orthodontic force for 12 weeks. Four beagles extracted the fourth premolar. After 12 weeks, the third premolars were moved distally with 30 or 150g orthodontic force as control group. The characters about the third premolar movement -3- 上海交通大学 2005 级口腔临床医学硕士学位论文 style, movement rate, external apical root resorption, and alveolar bone remodeling were investigated by following methods: measuring the distance of tooth movement, radiographic examinat