可显影软腭植入材料的制备及性能分析-preparation and performance analysis of developable soft palate implant material.docxVIP

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可显影软腭植入材料的制备及性能分析-preparation and performance analysis of developable soft palate implant material.docx

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可显影软腭植入材料的制备及性能分析-preparation and performance analysis of developable soft palate implant material

Results:This palatal implants material can be displayed precisely under X-ray. During the experiment, there were not obvious inflammations found.Histological analysis demonstrated thicker fibrosis with development in all specimens. At the beginning, more fibrosis was observed in PET. At the end of the experiment, the formation of capsule in PET ended up with a thickness of (18±4.1)μm, slightly thicker than that of HA-P (17±4.4)μm (P0.05). There were no obvious distinction between two groups.SEM photomicrographs of the HA-P revealed extensive pores which were roughly spherical in shape and evenly distributed throughout. The pores appeared connected to each other, forming an interconnected network Results obtained from measurement indicated a porosity of about 80%, and a controllable pore size in range of 500μm. During the process, the pH and mass display a gradual descent However, the pH indicator maintained a fairly stable range near to original enviroment. In addition,there was slowing decrease in mass relative stability compare to beginning.Conclusion:This palatal implants material can be displayed clearly under X-ray. The effectiveness can be maintenance in long-term.PET and HA-P stiffen the soft palate equivalency.HA-P possesses high porosities and well biostability. Basically meet the requirements of clinical application. It can be an ideal composite scaffold for tissue engineering and palatal implant.KeyWord: Sleep apnea-hypopnea syndrome; Obstructive; Palatal implant; poly (lactide-co-trimethylene carbonate); hydroxyapatite; visualized; fibrosis; biodegradability:缩写词表HAhydroxyapatite羟基磷灰石PLA-TMCPoly(lactide-co-trimethylene carbonate)聚乳酸- 三亚甲基碳酸酯PETPoly(ethyleneterephthalate)聚对苯二甲酸乙二酯PLApolylactid acid聚乳酸HAPhydroxyapatite-poly (lactide-co-羟基磷灰石－聚乳酸trimethylenecarbonate)－三亚甲基碳酸酯OSAHSObstructive sleep apnea-hypopnea syndrome阻塞性睡眠呼吸暂停低通气综合征UPPPUvulopalatopharymgoplasty悬雍垂腭咽成形术学位论文原创性声明本人郑重声明：所呈交的学位论文，是本人在导师的指导下，独立进行研究工作所取得的成果。文中依法引用他人的成果、对本文的研究作出重要贡献的个人和集体，均已在文