布地奈德福莫特罗吸入剂对老年COPD稳定期患者生活质量影响.docVIP

布地奈德福莫特罗吸入剂对老年COPD稳定期患者生活质量影响 　　[摘要] 目的 评估布地奈德／福莫特罗吸入剂治疗老年COPD稳定期患者的疗效。 方法 COPD患者93例，采用SF-36健康调查量表进行生活质量评估。 结果 SF-36总评分60岁组、大专以上学历和月收入≥1000元的患者明显高于组内其他组，差异有统计学意义（P ＜ 0.05）；治疗组患者PF、RP、BP、GH、VT、MH和总评分均明显高于对照组，差异有统计学意义（P ＜ 0.05）；药物治疗和月收入≥1000元是影响SF-36总评分的因素。 结论 布地奈德／福莫特罗联合吸入剂可以有效改善患者临床症状，提高患者生活质量。 　　[关键词] 布地奈德；福莫特罗；COPD；生活质量 　　[中图分类号] R563 [文献标识码] B [文章编号] 1673-9701（2012）04-0090-02 　　 　　Influence on the quality of life by Budesonide/Formoterol inhalant in treatment of elderly patients with stabilization COPD 　　GU Liang ZHAO Tian WU Jinyan QIN Guangyue 　　Department of Respiratory Medicine of Zhejiang Hospital, Hangzhou 310013, China 　　[Abstract] Objective To evaluate the curative effect of budesonide/formoterol inhalant in treatment of patients with COPD in stable of old age. Methods All of 93 patients with COPD were used the SF-36 health survey questionnaire to evaluate the life quality. Results SF-36 total score in 60 years old group, college degree or above and month income above of ￥1000 in the group were higher than other groups, and the difference was statistically significant (P ＜0.05); The RP, PF, BP, GH, VT, MH and total score in treatment group were significantly higher than that of the control group, and the difference was statistically significant (P ＜0.05); The treatment medicine and month income above of ￥1000 were the influenced factors of SF-36 total score. Conclusion Budesonide/formoterol inhalant can effectively improve the clinical symptoms, and improve the quality of life of the patients. 　　[Key words] Budesonide; Formoterol; COPD; Quality of life 　　 　　慢性阻塞性肺疾病（chronic obstructive pulmonary diseases，COPD）在美国居死亡原因的第5位，是一种慢性进行性气道阻塞性肺疾病，部分伴有气道高反应性。我院逐步将吸入型激素用于COPD的治疗，并取得了很好的效果，改善了患者的临床症状和生活质量，现报道如下。 　　1 资料与方法 　　1.1 一???资料 　　2009年1月～2010年12月来我院呼吸内科住院治疗慢性阻塞性肺疾病（COPD）患者93例。纳入标准：年龄≥60岁；无支气管哮喘、慢性心力衰竭及肿瘤疾病；未进行糖皮质激素治疗；无吸烟史。所有患者均能够坚持治疗并得到患者和家属同意。入选患者分为对照组43例，治疗组50例。 　　1.2 方法 　　患者入院后进行抗感染及对症治疗，进入稳定期后，对照组常规服用小剂量氨茶碱和短效β2受体激动剂，治疗组在对照组治疗的基础上给予联合吸人布地