冠醚与主客体化学.pptVIP

第一章，冠醚与主客体化学;Discovery of crown ether is quite important for the birth of supramolecular chemistry. (ether: 醚) Charles J. PedersenJournal of the American Chemical Society, 1967, 89, 2495. JACS, 《美国化学会志》 Cyclic polyethers and their complexes with metal salts 环形聚醚及其与金属盐的复合物 ------------------------------------------------------------------------- D. J. Cram developed this concept to cover a wide range of molecular systems and established a new field of chemistry, host–guest chemistry, where the host molecule can accommodate another molecule, called the guest molecule. 主客体化学 ------------------------------------------------------------------------- In 1978, J. M. Lehn attempted to organize these novel chemistries, and first proposed the term “supramolecular chemistry”.;诺贝尔化学奖1987The Nobel prize in chemistry 1987; Molecular chemistry, the chemistry of the covalent bond, is concerned with uncovering and mastering the rules that govern the structures, properties and transformations of molecular species. (mo′lecular, ′molecule; covalent bond: 共价键) Supramolecular chemistry may be defined as “chemistry beyond the molecule”, bearing on the organized entities of higher complexity that result from the association of two or more chemical species held together by intermolecular forces. “超越分子范畴” 超分子化学可定义为“分子之外的化学”，是关于两个或两个以上的化学物种通过分子间力缔合在一起而形成的具有更高复杂性的有组织实体；也包括：一个或同样分子的特殊部分的联合作用。;Supramolecular chemistry may be divided into two broad, partially overlapping areas: -- supermolecules are well-defined oligo molecular species that result from the intermolecular association of a few components (a receptor and its substrate(s)) following a built-in Aufbau scheme based on the principles of molecular recognition; 超分子：几个组分（一个受体及一个或多个底物）在分子识别原理的基础上按照内装的构造方案通过分子间缔合而形成的含义明确的、分立的寡聚分子物种。 -- molecular assemblies are polymolecular systems that result from the spontaneous association of a non-defined number of components into a specific phase having more or less well-defined microscopic