谭copd慢性支气管炎课件.pptVIP

* 前面提到，COPD发病与肺部对有害颗粒或气体的异常炎症反应有关，并伴有显著的肺外效应 其肺外效应与患者疾病的严重性相关。从这张图我们可以看出，COPD患者体内可以发生全身炎症反应，从而导致多个靶器官受累，包括肌肉、骨骼、心脏等。 * 随着年龄的增加，COPD的发病率呈现上升趋势，这是不可干预的因素，但研究发现，。。。。。。等是可干预因素，重在早发现，可以阻断或延缓疾病的发展。 * . * Exacerbations of COPD are a major cause of morbidity, mortality and hospital admission.1,2 Some patients are particularly susceptible to developing frequent exacerbations, an important determinant in health-related quality of life.1–3 The downward spiral of more frequent exacerbations can lead to decline in lung function; greater anxiety; worsening quality of life; social withdrawal; more exacerbati