一种光纤spr传感器设计及实现-design and implementation of an optical fiber spr sensor.docxVIP

摘要表面等离体激元共振传感器是一种新型的高精度传感器，主要用于生物学检 测、药物筛选、环境监测等领域，具有检测过程方便迅速、无需标记、检测前后 保持生物分子活性以及检测精度高等优点，配合适当的耦合介质和检测方法可以 实现实时监测。表面等离体激元共振传感器根据调制量的不同可以分为角度调制 型、波长调制型和相位调制型；根据耦合介质的不同可以分为棱镜型、光纤型和 光栅型。根据课题要求，本文主要研究波长调制的光纤表面等离体激元共振传感 器及由其构建的检测分析系统。文章首先简要介绍等离体激元共振传感器的相关概念，从理论上分析产生表 面等离体共振的条件，引出棱镜型表面等离体激元共振传感器的结构及工作原理, 在此基础上介绍光纤表面等离体激元共振传感器的结构及其特点。分析现有光纤 表面等离体激元共振传感器的不足，提出改进方案，并根据理论分析确定传感器 结构参数，对光纤结构进行加工重塑。采用这种传感器建立检测系统，包括光学 匹配系统和相关软硬件测试系统，以及后续的 MATLAB 数据处理等，通过获取的 光谱对环境介质进行检测。光学匹配系统主要实现将光源的杂乱光调整并耦合到 光纤中；软件测试系统主要实现控制检测系统中各部件有序规范的工作，并对数 据进行初步处理，包括噪声滤除、信息提取、曲线绘制以及数据存储；硬件测试 系统主要用于控制各个硬件设备，包括卤钨灯、蠕动泵和光谱仪，以及相关的硬 件电路；MATLAB 数据处理主要用于对 SPR 数据的滤波分析等工作。文章对光纤表面等离体激元共振传感器及其检测系统进行了研究，为此种传感器的改进、具体应用以及产品化奠定了一定的基础。关键词：表面等离体激元共振，光纤，生物传感器，数据分析ABSTRACTSurface plasmon resonance (SPR) sensor is a new transducer with high precision, which is mainly used in fields such as biological detection, drug screening and environmental monitoring. SPR sensor has many advantages, e.g., convenient, no-labeled, non-invasive and high-sensitivity. Combining with some coupling mediums and detection methods, the sensor can be used for real-time monitoring. Three main modulating methods based on angle, wavelength, and phase can be used for SPR detection. According to different coupling mediums, the sensor can also be divided into prism, optic fiber, and grating types. In order to realize the researching object, an optic fiber SPR sensor and a detection system based on it are mainly studied.In this paper, some concepts about the SPR sensor are introduced at first. The theoretical analysis of the condition to induce SPR phenomenon has been carried out. The structure and working principle of the prism based SPR sensor is presented, and on this basis the structure and working principle of optic fiber based SPR sensor is introduced. In order to overcome the shortcoming of existing optic fiber based SPR sensors, a new design is presented. The structural parameters of this new device are decided by theoretical analysis, and the struct