常见心血管疾病预防与治疗ppt课件.pptVIP

* * * * * 前面我们谈到一些逆转动脉粥样硬化的方法，那么，接下来还有一个问题，对这些已经引起明显临床症状的动脉粥样硬化进行治疗，是不是最好的避免临床事件的治疗方式？我们是不是可以在更早期预防动脉粥样硬化的发生，而不是等到动脉粥样硬化已经发生之后，再用各种干预手段去逆转它，也就是说，对我们的动脉进行投资，在更早的阶段干预各种危险因素，去预防动脉粥样硬化的发生。 * * * Emberson J et al, used estimates of the relative risk reductions from meta-analyses of randomised trials in combination with data from a prospective observational study of CVD (the British Regional Heart Study) to analyse the impact of different risk reduction strategies in primary prevention. The study examined the effects of prevention strategies based on single risk factor assessment or total risk assessment. They concluded that assessment of overall risk leads to more effective intervention than assessment based on single risk factors. Furthermore, multiple interventions have considerably greater benefits than interventions based on targeting single risk factors. Ten percent reductions in long-term mean blood cholesterol and BP could have reduced major CVD by 45%. Jackson R et al, conducted a review of the randomised trials of BP or blood cholesterol lowering treatments and outlined the rationale for targeting BP and blood cholesterol lowering therapy to patients at high absolute CV risk. They concluded that separate management guidelines for raised BP and blood cholesterol need to be replaced by integrated CV risk management guidelines. They also posited that because CV risk factors interact with each other, moderate reductions in several risk factors can be more effective than major reductions in one. References 1. Emberson J, Whincup P, Morris R, Walker M, Ebrahim S. Evaluating the impact of population and high-risk strategies for the primary prevention of cardiovascular disease. Eur Heart J. 2004:25:484-491. 2. Jackson R, Lawes CMM, Bennett DA, Milne RJ, Rodgers A. Treatment with drugs to lower blood pressure and blood cholesterol based on an individual’s absolute cardiovascular risk. Lancet. 2005;365:434-441. * * Smoking Affects the Entire Body The list of diseases and