Drugs for CNS degenerative disorders治疗中枢神经系统退行性疾病药物（可编辑）.docVIP

Drugs for CNS degenerative disorders治疗中枢神经系统退行性疾病药物 Drugs Used for Neurodegenerative Diseases of CNS Neurodegenerative Diseases Associated with progressive loss of neurons and their functionsParkinson’s disease帕金森病Alzheimer’s disease阿尔茨海默病Huntington’s disease亨廷顿病,舞蹈病Amyotrophic lateral sclerosis 肌萎缩侧索硬化症 Common Mechanisms of NeurodegenerationMisfolded and aggregated proteins?-synuclein in PD; ?-amyloid and tau in AD; huntingtin in HD; SOD and TDP-43 in ALS? Excess glutamate in the brain Impairment in the capacity of neurons for oxidative metabolism Parkinsonism Park