医学课件儿童艾滋病的抗病毒治疗_1.ppt

* If childern have active OIs, treat Ois first then start ART, * Process, Here are orphanage so we talked about the usual rules, if u can * If u get the score like 90, u may think it is good ,but for art u need more, what is means 95% * ART dosage is according to the weight , and growth chart, go through quickly, ARVs side effect so CBC LFTs are important to F/u ,routine f/u , routine immunozation should be done for ev ery child. * For small children, they can not take pills and tablelets so the syrup and liquid are available, D4T should be stored in fridge * * 每次随访随访又要测量体重，根据体重调整剂量 Short term /long term side effect; light /severe side effect * * Slide #24: Clinical Photo of Drug-Induced Rash insert titke This is an example of a drug-induced rash. This rash manifests as an erythematous, maculopapular, pruritic, and confluent rash. Reference Carr A, Cooper DA. Adverse effects of antiretroviral therapy. Lancet. 2000;356:1432-1330. * Slide #30: Long-Term Complications Associated with Antiretroviral Therapy Long-term complications associated with ART include abnormalities of the peripheral nervous system, metabolic changes, potential alterations in risk factors for cardiovascular disease, and morphologic changes. Many of these complications have emerged as a result of longer survival, decreased occurrence of OIs, and exposure to HAART. * 神经系统的发育表现在其说话时间，上学情况等 * * Back home in Colorado I use this photo to describe the stages of HIV. Here the higher you go, the lower the CD4 (as an alternative image). The tan grasses inn the foreground are 500 CD4’s (Stage 1). Go for a hike? All you need is water and a snack. (Positive living). The woods just past the lake are CD4 200-500 ( about Stage 2) also pretty safe but might need a warmer layer, more food ( more precautions with safe water, malaria nets, option of Cotrim, etc.) . The treed area on the mountain side are CD 4 200 (Stage 3-4), an area of more risk demanding more protection: warmer clothes, bet