Computational methods for microwave medical imaging微波医学成像的计算方法.ppt

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Computational methods for microwave medical imaging微波医学成像的计算方法.ppt

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Computational methods for microwave medical imaging微波医学成像的计算方法

2004-12-22 Qianqians PhD Thesis Defense computational methods for microwave medical imaging Ph.D. Thesis Defense Qianqian Fang Thayer School of Engineering Dartmouth College, Hanover, NH, 03755 Exam Committee: Professor Paul Meaney Professor Keith Paulsen Professor William Lotko Professor Eric Miller Outline Overview Forward field modeling accuracy and efficiency Implementation of the FDTD method 3D microwave imaging System and results Reconstruction efficiency Estimation model The adjoint method and the nodal adjoint approximation SVD analysis of the Jacobian matrix Phase singularity and phase unwrapping Scattering nulls Dynamic phase unwrapping in image reconstruction Conclusions Characteristics of Dartmouth Microwave imaging system Tomography, wide-band operating frequency, small target, lossy background, simple antenna Modeling nonlinear scattered field, nonlinear (iterative) parameter estimation Advantage of accessing in vivo data (small animal/patient breast imaging), first clinical microwave imaging system in the US Nonlinearity Nonlinearity between the measurement and the property: Forward problem is nonlinear Inverse problem is nonlinear Specific aims Improving image reconstruction performance: forward modeling accuracy (3D imaging) and efficiency, explore the balance point, generalized dual-mesh reconstruction quality/efficiency improvement: correctness of the estimation model, multi-frequency measurement data, adjoint method and nodal adjoint approximation In-depth understanding of nonlinear tomography impact of noise, resolution limit, optimization of system configuration Scattering nulls and math of phase unwrapping Forward field modeling efficiency 2D scalar FE/BE method: 2D scalar model requires approximations The coupling between the FE/BE equations increases the programming complexity, BE method: accurate (compared with approximated BC), but enlarges the bandwidth of the combined system FDTD (Finite Difference-Time Domain) method in microw