Processing Diffusion Weighted MRI Images：弥散加权MRI图像处理.pptVIP

Processing Diffusion Weighted MRI Images Diana R. Palsetia Shilpa R. Panth ECE 533 INTRODUCTION Lung MRI using Hyperpolarized Helium-3 - visualize defects in the lung In Diffusion Weighted Imaging (DWI) water protons diffuse The path traveled by the proton along any one direction can be given by: Where is observation time ADC Apparent Diffusion Co-efficient is proton displacement DWI-MRI on human lung ADC values probe lung microstructure DW Images – High Signal Intensity in the major airways High Signal intensity skews ADC mean value of lung parenchyma Segment out the airways APPROACH Thresholding Erosion/Dilation Binary Mask Erosion/Dilation Multiply with Original Image THRESHOLDING EROSION - DILATION BINARY MASK RESULT SOLUTION GUI CONCLUSION / FUTURE WORK CONCLUSION Manual segmentation provided better results compared to automation based on the analysis FUTURE WORK Combine the manual regional analysis with the GUI (not in the scope of the project) REFERENCES MR Imaging of Diffusion of He-3 Gas in Healthy and Diseased Lungs – Saam et.al. MRM 44: 174-179 (2000 ) Dynamic functional lung MRI using hyperpolarized gases Albert, M.S.; BMES/EMBS Conference, 1999. Proceedings of the First Joint, Volume: 2, 13-16 Oct. 1999, Pages: 1327 vol.2 PROBLEM Diffusion weighted Image of central slice showing the major airways Original Image Thresholded Image Applied Threshold based on the maximum intensity value Lost some lung parenchyma Eroded Image Dilated Image a b Dilated Image b Eroded Image a Figure 2: Binary Mask after Erosion and Dilation Figure 1: Binary Mask after Dilation and Erosion Application of Binary mask on: - Dilation followed by erosion (Figure 1) - Erosion followed by dilation (Figure 2) Erosion followed by dilation Dilation followed by erosion Multiplying the original image with the image obtained from the mask - Erosion followed by Dilation - Dilation follow