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Implications of Antibiotic Resistance in Nosocomial ... - Sullivanfiles课件.ppt

Implications of Antibiotic Resistance in Nosocomial ... - Sullivanfiles课件.ppt

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Implications of Antibiotic Resistance in Nosocomial ... - Sullivanfiles课件

Implications of Antibiotic Resistance in Nosocomial Infections and Livestock Production 324 SRP Conference Tyson Burkle Shane Schatz Gregory Danzeisen Chad Walock Individual Topics The Emergence of Antibiotic Resistance Chad Walock The Effects of Antibiotic Resistance on Nosocomial Infection Shane Schatz The Agricultural Effects of Antibiotic Resistance Tyson Burkle The development of novel antibiotics for the treatment of multi-drug resistant bacteria Greg Danziesen The Emergence of Antibiotic Resistant Bacteria Chad Walock English 324 Antibiotic Abuse Doctors often over prescribe Antibiotics Antibiotics are not needed every time youre sick Radetsky Story A doctor’s perspective. Dr. Mario??? Very Poor Doctor! Throws antibiotics at every virus he encounters. In real life these viruses wouldn’t even be affected. Antibiotic Misuse People often only use antibiotics until they feel better. Agricultural Abuse of Antibiotics Farmers overuse antibiotics in livestock. Antibiotics are given to the all animals even if only a few are sick. Baytril treats E. coli infections in turkeys. 3 Methods Genetic Recombination Transduction Exchange of genes through a bacteriophage. Transformation A bacterium picking up DNA from the environment. Conjugation Exchange of genes between 2 bacteria using a pilus. Evolution of Antibiotic Resistance Possible Resistance Mechanisms Efflux pumps Production of substances that inactivate the antibiotic Change target morphology (amino acid changes, methylation, etc. Increase production of the antibiotic’s target protein Prevention of antibiotic entry Thank you for your time. I will now field any questions. Effects of Antibiotic Resistance on Nosocomial Infections Shane Schatz English 324 Routine Operation Nosocomial Infections Nosocomial – Hospital Acquired Brief History of Nosocomial Infections Hospital Cause of Antibiotic Resistance Severity of Nosocomial Infections What we can do to prevent antibiotic resistant nosocomial infec

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