(双语)第十二章 T淋巴细胞介导的细胞免疫应答(双语)PPT.ppt

四、抗原特异性T细胞克隆性增殖和分化 多种细胞因子如IL-2、IL-4、IL-6、IL-7、IL-12、IL-15、IL-18、IFN-γ等参与T细胞增殖和分化过程，其中最重要的是IL-2。 Proliferation and differentiation of Ag specific T cells ⒈ CD4+T细胞的增殖分化 Th0 cell Th1 cell Th2 cell Tregs Th17 cell Memory T cell IL-12 IFN-? IL-4 IL-1β IL-6 IL-23 Proliferation and differentiation of CD4+ T cells ⒉ CD8+T细胞的增殖分化 CD8+T cell Proliferation and differentiation of CD8+ T cells cytotoxic T cell Memory T cell Activation and differentiation of CD8+T cells CD4+Th-independent pathway Target cells are professional APCs, they express costimulatory molecules at high level. So naive CD8+T cel