13 遗传咨询2008PPT.ppt

遗传病的防治Prevention and Therapy of Heriditary Disease;遗传咨询;*;*; 2.具有染色体畸变家族史的个体； 21/21 同源染色体间易位 ;Four siblings with testicular feminization syndrome. All four subjects in this photograph have 44 autosomes plus an X and a Y, (so they are genotypically MALES (!)) , but they have inherited the recessive sex-linked allele conferring insensitivity to androgens (male hormones). ;*;*;Chromosome Fra X AR等单基因病 多基因病 环境因素;Coarse facial features Malformed, large ears Long, narrow faces Very large testicles;*;*;*;*;*;*;*;*;*;*;*;*;*;*;*;*;*;*;*;*;*;*;正常;*;*;杨保胜 新乡医学院基础医学院 ybs@x