论文某院633例Ⅰ类切口手术围术期抗菌药应用合理性分析.docxVIP

目录摘要：1关键词：1Abstract:1Key words :21 资料与方法21.1 资料来源21.2 研究方法22 结果22.1 一般情况22.2抗菌药使用情况32.2.1抗菌药物种类32.2.2抗菌药应用时机和术后用药32.2.3联合用药情况42.2.4用法用量情况43 讨论43.1预防用药的适应症43.2预防用药的选择43.3预防用药的时机53.4预防用药的疗程5参考文献6文献综述7致谢11某院633例Ⅰ类切口手术围术期抗菌药物应用合理性分析摘要：目的:了解并评价某院633例Ⅰ类切口手术围术期抗菌药物预防性使用情况。方法:随机抽取该院2012年1月-2013年12月出院的633例3种Ⅰ类切口手术围术期抗菌药物使用情况进行调查及分析。结果：633例患者中,93例预防使用了抗菌药物,总预防用药率14.7%（93/633）。预防用药使用率最高的前3类抗菌药物为第一代头孢菌素类（79.6%）、青霉素类（6.45%）、第二代头孢菌素类（5.38%）；应用频率最高的前3位抗菌药物为五水头孢唑啉钠（46.2%）、头孢硫脒 (33.3%) 头孢替安 (4.30%)。术前2h给药2例（2.15%)，术前0.5～2 h给药62例（66.7%），术后当天给药29例（31.2%）；93例术中均未追加给药；64例预防用药一次，术后及时停用，术后用药时间24小时的20例（21.5%），用药疗程48小时的9例（9.68%），术后用药均为预防性用药。预防用药总合理率66.7%（62/93）。结论:该院I类切口预防用药情况较好，但仍然有用药不合理情况存在，用药指征把握不严、术前给药时机不够精确、术后给药时间过长等问题，还有待进一步加强管理。关键词：Ⅰ类切口手术; 围术期; 抗菌药物Rationalanalysis ofa hospital633 cases oftype Ⅰincisionperioperativeantimicrobial agentsStudent majoring in Pharmacy Zhang XuyanTutor Pang JieAbstract:Objective:To identify and evaluate the reasonable analysis of perioperative application of antibacterial drug in 633 cases of typeⅠincision operation. Method: Randomly selects 633 cases medical records of 3 types Ⅰ incision operation from January 2012 to December 2013 to research and analyze. Results:93 cases of the 663 patients used antibiotic prophylaxis and antimicrobial drug usage was 14.7%. The top three antibiotics were first-generation cephalosporins, Penicillin and second-generation, which accounted for 79.6%, 6.45% and 5.38%, respectively. The top three antibiotics in application of frequency were five water cefazol (46.2%),cefathia-midine(33.3% ),cefotiam (4.30%). Timing of the first dose of antibiotics administered: 2h before operation occupying 2 cases, 0.5-2h before operation occupying 62 cases and the day after postoperative occupying 29 cases, accounting 2.15%, 66.7% and 31.2%, respectively. All 93 cases of patients were no given the second dose of antibiotics. 64 cases just used antibiotic prophylaxis once and stoped taking durg after postoperative. 20 cases of medication