猫下尿道病课件.ppt

猫下泌尿道疾病的食物疗法 Dr. med. vet. Laurie Bucher WALTHAM Centre for Pet Nutrition 猫下泌尿道疾病的发病率有多少？ (LUTDs) 猫发病率及死亡率 LUTDs 猫 LUTDs的症状 排尿异常 停用猫沙盆 血尿 尿闭 尿频 +/尿道阻塞 无特异性症状 引起症状的原因 ? 53只猫尿道阻塞病因 非阻塞性病因 LUTD（109 只猫） 10岁以上猫 LUTD的病因 猫 LUTDs的重要病因分析 非特异性病因 60%+ 尿道结石 草酸钙及鸟粪石 尿道阻塞 鸟粪石为主 其他病因 anatomic abnormalities, behaviour problems Diagnosis of LUTDs in cats Urinalysis Crystalluria Urinalysis Crystalluria Haematuria Urinalysis Crystalluria Haematuria Pyuria Diagnosis of LUTDs in cats Diagnosis of LUTDs in cats Is dietary modification relevant in the management of LUTDs in cats ? Is dietary modification relevant in the management of LUTDs in cats ? Dietary ingredients and feeding patterns can influence urine pH urine volume urinary solute concentration Dietary modification can be used to …. Dissolve and prevent recurrence of struvite uroliths Prevent reformation of the mineral (struvite) component of urethral plugs may reduce recurrence of obstruction Reduce the risk of recurrence of calcium oxalate uroliths Reduce the recurrence of signs in cats with idiopathic cystitis What is saturation ? The degree of saturation of the urine provides the “driving force” for crystal formation Supersaturated urine has the potential to cause crystal precipitation In highly supersaturated urine precipitation will occur more readily pre-formed crystals will grow faster Zones of supersaturation and crystallisation behaviours Management of sterile struvite uroliths Nutritional goal - undersaturation of urine struvite RSS 1.0 Management of sterile struvite uroliths Acidification of urine to pH 6.0 - 6.5 Enhancement of urine volume / decrease of specific gravity to ~ 1.035 Restriction of dietary mineral content magnesium 0.03 - 0.08 g / 400 kcal phosphorus 0.5 - 1.0 g / 400 kcal Management of sterile struvite uroliths Feline S/O Control pHormula (canned) struvite RSS 0.58+0.18 Management of calcium oxalate uroliths What are the risk factors for calcium oxalate urolithiasis in cats ? Possible risk facto