《精确麻醉》ppt课件.pptx

精 确 麻 醉;精确麻醉;麻醉深度的精准监测; Covidien Respiratory and Monitoring Solutions | Confidential; Covidien Respiratory and Monitoring Solutions | Confidential;Hugh C. Hemmings，Talmage D. Egan. Pharmacology and Physiology for Anesthesia ;最小肺泡气浓度（Minimum Alveolar Concentration, MAC）;本定义具有下列几个要素：1、是肺泡气中吸入麻醉药的浓度;四、广义的MAC值;（一）MAC苏醒（MAC awake）;（二）MAC插管（MAC intubation）;（三）MAC应激（MAC BAR）;MAC;精确给药;15分钟后分压基本相等;Hugh C. Hemmings，Talmage D. Egan. Pharmacology and Physiology for Anesthesia ;a single 300-μg bolus, three 100-μg boluses every 20 minutes, an infusion of 300 μg at a constant rate over 1 hour.;适合精确麻醉的药物;吸入麻醉药;吸入麻醉药;The rate at which the alveolar concentration (FA) approaches the inhaled concentration (FI);持续泵注达到稳态血药浓度;持续泵注后的清除半衰期;持续泵注后清除半衰期;用药个体化的问题;Hugh C. Hemmings，Talmage D. Egan. Pharmacology and Physiology for Anesthesia ;Case ;进入手术室; HR 76bpm, ABP 177/89mmHgCVP 14mmHgCO 1.9L/minSV 25ml;200ml;TCI： 2 ug/ml -- 1.3ug/ml;协同作用;精确麻醉;感谢聆听