生理学双语课件 第五章 呼吸.ppt

Factors affecting oxygen dissociation curve ? Carbon dioxide transport * Forms of transport Physically diffusion Combination with Hb HCO3? HHbNHCOOH * Carbon dioxide dissociation curve * Influence of combination of Hb with O2 on CO2 transport (Haldane effect) Carbon dioxide transport in the blood Carbon dioxide dissociation curve * Chapter 5 RESPIRATION Introduction ? Containing: inspiration expiration ? Functions: Obtain O2 from external environment Remove CO2 form the body ? Respiratory processes: Pulmonary ventilation Gas exchange in the lung Gas transport in the blood Gas exchange in the tissue Respiratory processes § 1. Pulmonary ventilation ? Definition ? Principles of pulmonary ventilation * Driving force Direct ~: pressure changes in alveoli Source ~: contraction of respiratory muscles Inspiratory muscles: Diaphragm, External intercostal muscle Expiratory muscles: Diaphragm, Ext- Internal intercostals Accessory respiratory muscles Respiratory movement Types of respiration ?Eupnea Forced breathing (Deep breathing) ?Abdominal Thoracic breathing Principles of pulmonary ventilation ?Contraction (Relaxation) of inspiratory muscles?Expansion (Reduction) of thoracic cavity?(?)Distension (Recoil) of alveoli? Intrapulmonary pressure?(?)() atmo- spheric pressure?Air flows into (out of) the alveoli Intrapulmonary pressure ?Inspiratory phase: 1 atm ?Expiratory phase: 1 atm ?At the end of inspiration or expiration: =1 atm Intrapleural pressure ?Concept Changes during respiratory cycle More negative as inspiratory processing Less negative as expiratory processing ?Measurement Expression Direct Indirect