乳腺型肌纤维母细胞瘤课件.ppt

mesenchymal adj.? [生]间叶细胞的,? 由间叶细胞组成的,? 间叶细胞样的 * recognition：n.??承认,?认出 * Incidental: adj.??附带的,?非主要的,?偶然的,?容易发生 * Postulated: n.??假定 putative Gynaecomastia: 男子女性型乳房 * contour :轮廓 fascicles ：束状 stroma 基质，子座 mast cells :肥大细胞 conspicuous:显著的 prominent:杰出的，突出的 mimics: vt.??模仿,?模拟 * Mammary-type myofibroblastoma 乳腺型肌纤维母细胞瘤  一、Definition 定义 A benign mesenchymal neoplasm 良性间叶性肿瘤 composed of spindle-shaped cells with features of myofibroblasts, 由梭形有肌纤维母细胞特征的细胞构成的 embedd in a stroma that contains coarse bands of hyalinized collagen 间质内含有玻璃样变的粗大胶原纤维条带 and conspicuous mast cells 可见大量的肥大细胞 and admixed with a variable amount of adipose tissue. 并伴有数量不等的脂肪组织。 the tumour is histologically identiacal to myofibroblastoma of breast. 其组织学特点与乳腺的肌纤维母细胞瘤相似。 二、Epidemiology 流行病学 Lesion have arisen in adults with an age range of 35 to 67years (median 55.5 years) and a male predilection(8males,2females). 发病年龄见于35-67成年人（平均55.5） 男性多见（8例男性，2例女性） The extrammary location of some myofibroblastomas has only recently been defined when 10 cases were reported. 乳腺外的肌纤维母细胞瘤直到最近才有10 例报告。 Therefore ,conclusions related to epidemiology could alter with increased tumour recognition 因此随着对肿瘤认识的增加，流行病学方面也会发生改变。 三、sites of involvement 受累部位 The most common location of mammary-type myofibroblastoma is the inguinal/groin area. 乳腺型肌纤维母细胞瘤最常见于会阴/腹股沟区域。 Other reported sites include abdominal wall，buttock ,back and vaginal wall. 其他部位有腹壁，臀部，背部和阴道壁。 Lesions arise most commonly in subcutaneous tissue. 最常见的发病部位是皮下组织。 However,cases have arisen deep to abdominal wall muscle ，in the posterior vaginal wall and in a paratesticular location . 但也可位于腹壁肌肉，阴道后壁和睾丸旁。 There is an apparent predilection for myofibroblastomas to arise along the putative anatomic “milk-line”that extends from axilla to medial groin. 肌纤维母细胞瘤明显好发于从腋窝至腹股沟中部的“白线” 四、Clinical fe