先天性肾源性尿崩症课件.pptVIP

Diseases Associated with G protein-Coupled Receptors Giving By wangnisha Xiexixiu Zhangwenshan Wangjing brief introduction The human genome may encode as many as 2000 different GPCRs. Their importance in human biology is reflected by the fact that more than one-quarter of all prescription drugs act as ligands that bind to this huge superfamily of receptors. A number of inherited disorders have been traced to defects in both GPCRs and heterotrimeric G protein . Several diseases Congenital nephrogenic diabetes insipid